Marfan syndrome (also called Marfan's syndrome) is a genetic disorder caused by the misfolding of the protein fibrillin-1. Fibrillin-1 is coded by the gene FBN1.
People with Marfan tend to be unusually tall, with long limbs and long, thin fingers. Marfan syndrome is a dominant genetic trait, meaning that people who inherit only one copy of the Marfan FBN1 gene from either parent will develop Marfan syndrome and be able to transmit it to their children.
Marfan syndrome has a range of expressions, from mild to severe. The most serious complications are defects of the heart valves and aorta. It may also affect the lungs, the eyes, the dural sac surrounding the spinal cord, the skeleton and the hard palate.
Notable people with Marfan Syndrome:
1. Javier Botet, who starred as Mama in the Mama movie, and the mutant from movie called "REC".
2.
Bradford Cox of Deerhunter, the lead singer.
3. Michael Phelps, American pro swimmer.
Source: http://en.wikipedia.org/wiki/Marfan_syndrome
Title :
Marfan Syndrome, a Genetic Disorder Makes Body Longer
Description : Marfan syndrome (also called Marfan's syndrome) is a genetic disorder caused by the misfolding of the protein fibrillin-1. Fibrillin-...
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